This study was conducted to evaluation of the pathogenesis of shvitra. It was randomized controlled study on 60 number of patients and was divided into three groups named Group A, Group B, Group C. Haridra churna was given to Group A, dose of Haridra churna 6gm twice a day with Luke warm water. Khadira churna was given to Group B, dose of Khadira churna 6gm twice a day with Luke warm water. Aragvadha churna was given to Group C, dose of Aragvadha churna 6gm twice a day with Luke warm water. After completion the treatment it was assessed by the use of subjective criteria like as percentage of area, colour of affected area, colour of hair of affected part, number of patches, maximum size of patches, Mandalotpatti, Shwetavarnta, Rasa, Rakta, Mamsa & Meda vaha srota dushti lakshana, itiching by giving different grades for its severity and objective criteria was used Hb%, ESR, RBS, SGOT, SGPT, LDL. Separate questionnaire was prepared to assess the clinical features of ‘Shvitra’. Observations were recorded before & after treatment of 45 days with follow up at every 15 days. After treatment showed that the Rasa dusti lakshana 12.50%, 64.71% and 58.14%, Rakta dushti lakshana 12.50%, 55% and 68.57%, Mamsa dushti lakshana 0.00%, 14.29%
and 54.55% , Meda dushti lakshana 5.88%, 10.53% and 76.19% was reduced by respectively in Group A, B & C. Finally it was observed that group B was more effective than Grop A and C.