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Journal of Ayurveda

A Peer Reviewed Research Publication of
National Institute of Ayurveda, Jaipur

TABLE OF CONTENT

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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Conceptual Studies

Prof. B. M. Hegde*

HOW MIGHT THE BENEFITS OF AYURVEDA BE COMBINED WITH MODERN MEDICINE?

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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ABSTRACT

Ayurveda, the science of life, (Ayu=life; vid=science) is a part of the ageless Vedic heritage of India. Ayurveda prescribes life style changes with emphasis on tranquility of mind that is filled with universal compassion, as an insurance against an occasional illness. In this system disease is only an accident. Immune boosting methods are the mainstay of Ayurvedic therapeutics. With advances in modern science and technology one cannot ignore the benefits of using modern hi-tech methods for emergency care. A judicious combination of modern medicine and Ayurveda would be an ideal training for a family doctor. More skilled specialists in either system could be used only at the referral point. This would bring down the top-heavy cost of modern medical care remarkably. More than eighty per cent of the illnesses are either minor or self-correcting. They could easily be helped using ayurvedic methods and a placebo doctor. In addition, Ayurveda could help chronic debilitating diseases to a great extent, at a very small cost to the taxpayer. Ayurveda would not be of much use in an emergency. About ten per cent of the time modern medicine becomes mandatory. Roughly ninety per cent of the unnecessary cost could be reduced for the benefit of all without detriment to public health. Rather, most of the iatrogcnic problems could thus be avoided.

Clinical Studies

*Prof. Ajay Kumar Sharma

Clinical evaluation of the role of Hridyarnava Rasa and Haritakyadi Churna in the management of ischaemic heart disease (Hridroga)

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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ABSTRACT

The present study was conducted on 5o clinically diagnosed and confirmed patients of IHD. Patients having I.H.D. with specific conditions were not registered. The study was conducted with an objective of evaluating the role of HRIDYARNAVA RASA AND HARITAKYADI CHURNA IN THE MANAGEMENT OF (HRIDROGA) with special reference to ISCHAEMIC HEART DISEASE on various scientific parameters. It was observed that there was significant improvement in clinical manifestations of I.H.D. after the therapy with HRIDYARNAVA RASA AND HARITAKYADI CHURNA. The level of S.cholesterol, LDL, V.L.D.L. and S.Triglycerides decreased and the level of H.D.L increased considerably after the therapy. Studies on parameters like E.C.G. and T.M.T have revealed that HRIDYARNAVA RASA AND HARITAKYADI CHURNA have potent activities on increasing blood supply to myocardium (Coronary Vasodilation effect) with significant improvement of ST changes. HRIDYARNAVA RASA AND HARITAKYADI CHURNA can be used effectively in the management/to slow down the progress of atherosclerosis leading to Hridroga (I.H.D.).

Clinical Studies

*Dr. Pooja Sabharwal, **Dr. M. Dinkar Sarnia, ***Dr. D. P. Agarwal

Effect of intervention ofAyurveda & Practical implementation of Shadchakras (Pranic Healing) An indigenous approach as co- therapy with Chemotherapy & Radiotherapy for physical & mental well being of cancer patients —A Clinical Study

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - cancer, shadchakras, pranic healing, ayurveda.
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ABSTRACT

Cancer a major killer, the most dreaded among diseascs,is fast engulfing the globe posing the challenge to the ingenuity of human beings. Patients Who present with cancer have basic options for treatment. The first and the most conventional treatments utilize chemotherapy, surgery and radiation. Second are a wide range of alternative therapies. Third is a combined approach .Conventional treatments for cancer have varying success rates. Statistics are available for the success and failure of treatments. A list of side effects for each treatment is also available. There has been considerably adverse effects like nausea, itching, emesis, fatigue and ultimately it deteriorated quality of life on physical ,functional, social and psychological domains. Hypothesis : Thus the present study was designed to evaluate the effects of herbal compound oncocare capsule and pranic healing alor g with radiotherapy in cancer patients. Materials & methods : The study was conducted in Bo patients who were suffering from cancer. Four groups were made. first was control group ; oncocare capsule was given in second group, third group receives only pranic healing techniques and group four receives both oncocare and pranic healing techniques .Patients were assessed on the basis of subjective and objective , biochemical and psychological parameters. Results: there was highly significant improvement in fourth group that is combination of herbal formulation along with stress management techniques.

Pharmaceutical Study

*Dr. Kishori Apte, **Dr. Mandar Akkalkotkar

Comparative Toxicology of commercial preparations of "Hingool" and "Kajjali" used in Ayurved.

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - "Hingool", "Kajjali"
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ABSTRACT

Red colored mercurial compound named cinnabar ("Hingool") found in ores has been used in Indian and Chinese traditional Medicine since long. Indian Vaidyas triturate equal amounts of processed (purified) sulfur and processed (purified) mercury to form black colored compound, named "Samagandha Kajjali" commonly called as "Kahan". "Kajjali" is used as adjuvant, stabilizer and bioenhancer in various metalloherbal preparations. "Kajjali" contains HgS, l'rocessed(purified)sulphur and organic matter. The acute and long term comparative toxicology of readily available commercial samples of "Kajjali" and "Hingool" were conducted as per OECD Guidelines at Rashtriya Visha Vidnyan Kendra, National Toxicology Centre, Pune. The acute oral toxicity data shows NO MORTALITY or any other clinical signs of intoxication upto 5000 mg/kg dose in mice when administered "Kajjali" and "Hingool". This dose of 5000 mg/kg is equivalent to an absolute Human dose of 38.790 g. The Human dose of 1000 mg/day/human converted to dose in mice was calculated as 130 mg/kg and 5- times the human dose converted to dose in mice was calculated as 650 mg/kg, have been administered to Swiss albino mice orally for 30 days. The findings of the long term studies have been discussed.

Pharmaceutical Study

*Dr Sunil Gupta, **Dr H. K. Kushwaha, ***Dr. Amita Jhunjhunwala, ****Dr. D. P. Agarwal

Taming the side effects of radiotherapy in oral carcinoma patients with help of Ayurvedic Medicine (Clinical Study)

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - Oral carcinoma, Side effects, radiotherapy, Formulation, brachytherapy, mucositis, anorexia and salivary reactions.
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ABSTRACT

The role of an ayurvedic formulation is evaluated to minimize the side effects of radiotherapy suffering from oral carcinoma in this study. 30 patients of oral carcinoma were taken for this study and divided in three groups of 10 patients in each group. Comparative study was done between three groups by giving radiotherapy alone in one group and ayurvedic formulation + Radiotherapy in other two groups at different intervals. Results suggested that there was significant reduction of the side effects in the patients who were taking Ayurvedic formulation along with Radiotherapy.

Clinical Studies

*Dr. Mukesh Kumar Meena, ** Prof. H. K. Kushwah

A Clinical Evaluation of Agnikarma In Sandhigata Vata W.S.R. To Cervical Spondylosis

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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ABSTRACT

Ayurveda ,the science of life has its own methodology and hypothesis to manage all kind of diseases. Sandhigata vata is one of the commonest joint disorder broadly coming under vata vyadhi and affects to the skeletal system in the geriatrics, because more vulnerability to dhatu kshaya at that span of life. vata dosha get provocated due to dhatu kshaya(degenerative process) or avarana prakriya and produces various types of vatic vyadhies. Now a days joint disorders are one of the main cause of distress after fourth decade of age. though medical science provides powerful analgesics and new surgical procedures, but due to side effects and further complications, the disease is as such remains as a challenge to medical fraternity.clinical study is most established method to revive all treatment hypothesis scientifically. Agnikarma is a para-surgical procedure, advocated by Acharya Sushruta for asthi, sandhi, sira and snayugata vata vikaras and it is highly effective without producing any further complications in comparison to modern surgical procedures. The drug Nirgundi and Shigru Yukt Trayodasanga Guggulu consisting Rasayana, Balya, Vatsamaka, Amapachana drugs are the best way to treat as well as control degenerative process (dhatu kshaya) in Sandhigata vata. Keeping all these facts in mind treatment modality of Sandhigata vata has been designed to equalize the efficacy by Agnikarma and Trayodasanga Guggulu.

Pharmaceutical Study

*Dr. Rajeev Kushwah, **Prof M.C.Sharma

Ashwagandha An Immunomodulator Drug

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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ABSTRACT

Man the super most of all the species is always remaining in the search of one prime goal: the perfect health. Ancient Acharyas and their counter parts in this era tried and still trying their best to keep the man young and virile. In Samhita period mean life span of human being is 100 yrs. But in present era in India life expectancy for the human 63 yrs. (P.S.M. 2005 ). As an answer to solve the problems of the healthful longevity including the mental development and resistant against diseases the Rasayan is their. There are so many Rasayan drug depicit in our Ayurvedic literatures which are responsible to improve immunity and increase life span.Ashwagandha is one of them. IgG increase after treatment up to 5.81 %-, Hb 5.15%-, RBC 2.57%-, WBC 5.56961, Neutrophil 1.53%T, Eosinophil .01%T, Lymphocytes 1.031, Weight 3.59%1 and all these parameter include in cellular & humoral immunity. Now this research shows that Ashwagandha plays an important role to increase immunity as well as acts as an anti-oxidant also.

Clinical Studies

*Dr. Amrita M. Mishra

Effect of Shatadhaut Gluit in the management of Pathological Leucorrhoea with special reference to Pittaj Yonivyapad Management of Pittaj Yonivyapad

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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ABSTRACT

Ayurved has elaborated Gynecological disorders under the entity of Yonivyapadas. Although Shwetpradar or yonigat Shwetsrava has not being depicted as a specific disease but it invariably occurs as a major symptom of several Yonivyapadas including Pittaj yonivyapada.. Pittaj dominance of this disease unquestionably expect drug that possess properties that are opposite to those of pitta, i.e. sheet, sukshma, madhur rasa, sheet virya, madhur vipaka, dahashaamak. It is also expected to be vranaropana, jeevanunashak (disinfectant). All the above properties are present in Shatadhaut Ghrit, So a Single blinded double- arm randomized clinical trial was conducted with 60 patients of childbearing age group from the same geographical area i.e. Wardha District, in 2 Groups. 1. Group A — 30 Patients subjected to local application of Fluconazole 2. Group B — 30 Patients subjected to local application of Shatadhaut Ghrit. There was significant to highly significant reduction in signs & symptoms in both groups but Burning, redness, regressed more spontaneously in Group. B. Percentage of recurrence was negligible in Group. B while it was more in Gap. A. Cervical erosion if present was found to recover very spontaneously in Group. B & not in GroupA. Shatadhaut Ghrit is highly effective in the management of Pittaj Yonivyapad. It increases local cell immunity and prevents recurrence of the disease.

Clinical Studies

*Dr. K. V. Narasmnha Raju

A Study on the effect of Sri Bahusala Gudam as Naimittika Rasayana in the management of Industrial Hazards w.s.r. to Tamaka Swasa

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - Sri Bahusala Gudam, Naimittika Rasayana, Industrial Hazards, Janapadodhwamsa, Tamaka Swasa, Occupational Asthma.
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ABSTRACT

Industrialization in any developing nation is bound to carry some associated hazards,due to polluted environmental elements like air, water, land and climate. Tamaka swasa forms one of the commonest industrial hazards of recent years and is considered as Occupational asthma. Industrialization and its hazards are explained through the concept of Janapadodhwamsa, an Epidemic condition, where Rasayana forms one of the basic treatment modalities. 15 patients from Chemical industry (Gr-A) and 15 from Cotton Industry (Gr-B) are selected for the study who were administered Sri Bahusala Gudam. Gr-B yielded Significant results than Gr-A which is expressed through marked changes in symptomatology and in Ig E levels.

Pharmacological Study

*Dr. Mundeep Jaiswal, **Dr. Pradeep K Prajapati, **Dr. B. Patgiri, ***Dr. B. Ravishankar

A comparative pharmacological evaluation of Shirisharishta prepared by bark, sapwood and heartwood of is lebbeck Benth

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - Shirisharislita, Albizia lebbeck Benth (Shirisha), Anti-asthmatic activity, Anti-tussive, CMI suppression, Anti-inflammatory
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ABSTRACT

"Shirisharishta" is a well known ay-urvedic fermented preparation of Albizia lebbeck Benth. renowned for its utility in the treatment of respiratory disorders. However, no information is available on which part would be ideally suited for its preparation. Hence three samples prepared using "twaku" (bark), "kastha" (sapwood) and "sure (heart wood), were subjected to comparative pharmacological investigations to assess the impact of formulation factors on the expression of pharmacological activity. The formulations were evaluated for immunomodulation, anti-tussive, anti-inflammatory and anti-histaminic activities. All the three formulations were found to be active in most of the experiments carried out though there was quantitative difference. The formulation prepared using heartwood was found to have best activity profile, specifically with reference to its therapeutic use in respiratory disorders. It exhibited anti-inflammatory, cell mediated immunity (CM I) suppressing, anti-tussive and anti-histaminic activity. The formulation prepared using sapwood exhibited anti-inflammatory, CMI suppression and moderate anti-tussive effects. The formulation prepared using bark exhibited only moderate CMI suppression and anti-tussive effects. The study clearly indicates that the part of the drug used for preparation and the formulation factors influence biological activity expression. A complementary phytochemical study showed presence of higher concentration of active principles in the most active formulation.

Clinical Studies

*Dr. Mahesh Verlekar, **Dr. Smruti R. Nagvenkar, ***Prof. Mahesh Chandra Sharma

Effect of Semecarpus anacardium Linn. (Bhallataka) in the management of skin diseases w.s.r to Psoriasis.

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - Psoriasis, Bhallataka, Semecarpus anacardium, kustha, Ointment
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ABSTRACT

The present study is aimed at the evaluation of effect of Semecarpus anacardium (Bhallataka) in the management of Psoriasis. The clinical trial was carried out in four groups. In Group - A Bhallataka was used internally & externally. In group - B SA Capsules were given internally. In group - C 5% SA ointment is used far external application and in Group - D Wrightia tinctoria oil was used. 10 patients were taken in each groups and the trial was carried out for one month. The results were evaluated on the basis of clinical findings and photographs taken before and after treatments. At the end of clinical trial the observations shows that 5% SA ointment is more effective than other Groups.

Conceptual Studies

*Dr. Chhagan Jangid,**Prof R. R. Dwivedi, ***Dr. Mahesh Kumar Vyas

Seasons, Not Stars, Steer Life

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

KEYWORDS - Kala, Seasonal fluctuation., Bala, Healthy-Volunteers
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ABSTRACT

Kala, the invincible and unavoidable causative factor influences the every aspect of all living as well as non-living beings right from the origin to end. It is accepted a unique & specific issue of all types of effects or disorders, in Ayurveda. Seasons are the part of Avasthika-Kala and are six in number in concern to India. The existence and well-being of all living beings depend on the continuous interactions and adjustment between their internal & external environmental factors. These external environmental factors are explained as seasonal fluctuations, which affects Bala of all living beings. The time of year we are born influences our personality as well as our health later in life. Therefore, to find out relationship between Bala (strength) & Date of Birth, 54 Healthy-Volunteers of age group 21 to 30 years, were selected from D.P.D. section of department of Basic-Principles; I.P.G.T. & R.A., Hospital; Jamnagar. A detailed Research proforma and scoring prototype was developed & used to calculate the Bala. The obtained results were supportive to the hypothesis and also statistically significant.

Conceptual Studies

*Dr. Archana Rai, **Dr. Nisha Gupta

Quantification of Ruksha, Sheeta and Chala Guna of Vata Dosha — An Instrumental study

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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In present scenario when accurate measurement and standardization is the need of the hour, Ayurvedic fundamentals should also be standardized to compete and stand strongly to cope up with the increasing demands of purity and enhancing potency in the international health strategy. Keeping this in mind, an effort has been done to measure the Vata dosha, in terms of its Ruksha, Sheetaand Chala guna. Vata is invisible but it can be traced out as Prana Vata in inspired and expired air. In this study Vata dosha pradhan Svasa patients were taken along with healthy subjects to measure the Ruksha, Sheeta & Chala guna of Vata Dosha and a comparative study was conducted in two groups having 30-3o subjects in each gr. The following methods and devices are adopted in this study. Questionnaire, Manually RR and PR counting, Spiro meter & Peak flow meter, DMMT, DMM, DINT, Recording of Minute ventilation and Data presentation and Statistical analysis. A real difference was obtained in properties of expired air in terms of Ruksha, Sheeta and Chala guna in between patients and healthy subjects. It can be concluded that in diseased condition Vata dosha acts as a pathological attribute due to vitiated Ruksha, Sheeta and Chala guna. This pioneering study shows that, this concept of evaluation of Doshas through their qualitative features can be used for scientific establishment of Ayurveda in new light.

Pharmaceutical Study

*Shubha H. S., Dr. R. S. Hiremath, ***Dr. B. S. Prasad

Toxicity Study of Tamra Bhasma

2008   |   October- December   |   VOLUME - II   |   ISSUE - 4

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Among vishas, Tamra is considered as more poisonous, because, it produces eight toxic effects, such as Bhrama, murcha, vedana, sweda, kleda, vanti aruchi, chittasantape. Copper toxicity leads to heamaturia, glomerulonephritis, gastro-intestinal distwbances, peripheral neuritis, and circulatory collapse, paralysis of limbs and atrophy of muscles, coma and even death. In spite of these properties Tamra Bhasma is widely used in the formulations like Arogya vardhini vati, Laxmi Vilasa Rasa, Hrudayamava rasa, Chandrakala Rasa, etc, which are commonly being practiced. Still there is a dilemma regarding safety and efficacy of Tamra bhasma. To establish its safety an experimental study was conducted on Swiss albino mice (weight 24-30 gms) of both the sexes and its LD5o, Oral acute & sub acute toxicity were assessed. . Toxicity study result shows that in LD5o, the doses ranging from 2orng-Lo-12 gm are observed as non-fatal. Oral acute toxicity study also shows rio mortality or toxic effects. In sub acute toxicity study all animals in all the 4 groups were normal, active and healthy during observational period. It is observed that, the medicinal group of 350 mg has shown alteration in biochemical findings i.e. WBC differential count showed increased percentage of Lymphocytes and decreased percentage of Polymorphs in blood.

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