ISSN:2582-7693

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Journal of Ayurveda

A Peer Reviewed Research Publication of
National Institute of Ayurveda, Jaipur

TABLE OF CONTENT

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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Editoral

* Vaidya Pawankumar Godatwar

Peer Review: an ancient Tradition

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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ABSTRACT

Peer review is defined as the process of review by qualified experts known as "peers," (experts in the same field) who identify manuscripts, research proposals, grants and other work(s) that are worthy of publication.' It is the process by which manuscripts submitted to health, biomedical, and other scientifically oriented journals and other publications are evaluated by experts in appropriate fields (usually anonymous to the authors) to determine if the manuscripts are of adequate quality for publication.' The peer review process attempts to set high standards on one hand and safeguards on the other to prevent the spread of unwarranted claims, unacceptable interpretations or personal views.

Editoral Forum

Philip E. Bourne*, Alan Korngreen**

Ten Simple Rules for Reviewers

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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Clinical Studies

*Dr Shikha Gupta, **Prof H.D. Khanna, ***Dr B.M. Singh

Treatment of Asthma in Children with Shvas-Kas-Chintamani Ras (SKCR)

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - Bronchial. Asthma, Shvas-Roga, Tamak-Shvas, SKCR (Shvas-Kas-Chintamani. Rasa), MDA ((Malondialdehyde), SOD (Superoxide dismutase), GSH-Px (Glutathione peroxidase), GGH (Ginger, Garlic and Honey)
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ABSTRACT

Most of the modern medicines of asthma no doubt can control the acute asthmatic symptoms, but do not cure the recurrent or frequently relapsed asthmatic (Tamak Shvas) cases. A commonly used herbo-mineral ayurvedic drug-SKCR was considered to cure such asthmatic cases with a specific Anupan-GGH. The clinical study was planned in two parts. The first, deals to study the assessment of effects of SKCR in patients of bronchial asthma (Tamak-Shvasa) in terms of improvement in signs & symptoms of asthma and second, deals with the assessment of antioxidant properties in terms of MDA, SOD and GSH-Px. Total 37 children, comprised 29 asthmatic children in clinical study part—I, and o8 healthy children were included for the study part-II. Total 29 children; age group between 2 to 12 years, irrespective of sex and having the signs and symptoms of breathlessness, cough, fever, running nose, chest pain, restlessness, wheeze & use of accessory muscle etc; were selected. The drug SKCR was given in a dose of 3-5 mg/kg/dose x 12 hourly with a specific Anupan- GGH in a ratio of 1:2:4 respectively for a total period of 45 days. The complete hemogram, AEC, LET and routine and microscopic examination of urine were carried out to study the effect of drug on the disease as well as its toxic effect, if any. The clinical response was observed based on the modified scoring system on 7"1 (1" —Follow up), 15th (2nd —Follow up), and 45th (3rd —Follow up) days after registration, while the estimation of serum MDA, SOD and GSH-Px at the time of registration, on 15th (1st —Follow up), and 45th (2nd —Follow up), days of treatment along with other investigations. Two to three dose of oral Deriphyllin (etophyllin and theophylline), 20 mg/kg/day along with SKCR, was given to few patients 'if needed' with a maximum period of first 2 days. Result of the study was found very encouraging in terms of improvement in clinical features (95%), reduction in serum MDA level, without any significant derangement in LET & trifle adverse reactions after 3rd follow up (45 days). After 6-month of given treatment, only five cases were relapsed. However, the relapsed rate in these cases was found significantly lower (1.2 ± 0.54 6 month) than the past history (5.4 ± 2.41)

Clinical Studies

*Dr. Madhavi Seetha, **Dr Omprakash Sharma, ***Dr. R.S Sharma

Dashmoola Siddha Ksheer Shirodhara in the management of Anidra w.s.r. to Insomnia

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - Anidra , Insomnia , shirodhara
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Shirodhara is a safe Sr effective treatment modality in the management of Anidra as it not only produces symptomatic improvement but also improves various mental faculties to produce significant improvement in sleep pattern of patients. Thus shirodhara (ksheerdhara) is a safe & effective treatment for Anidra (insomia).

Clinical Studies

* Dr. Hemanta Kumar Panigrahi, ** Dr. T. Bikshapati

Efficacy of Ayurvedic Medicine in the treatment of Oral Leucoplakia —A randomized, single blind study

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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This Study evaluates the efficacy of some Ayurvedic medicine in the treatment of Oral leucoplakia. 30 clinically and histologically diagnosed patients of oral leucoplakia were randomly selected from the 0.P.D of CRIA, New Delhi, for the study. All the patients were kept in a single group. The duration of Treatment was go days. The result was assessed both clinically and histologically. Post treatment follow-up was done for 2months. Clinically the patients had 56.7% complete remission, 33.3% had partial response.and in 10% of patients no progression was found. Similar results were also found histological. The observed results suggest that this regimen can be effectively and safely used for the management of oral Leucoplakia.

Experimental Studies

*Dr Sunil Gupta, **Dr H. K. Kushwaha, ***Dr Amita Gupta, ****Dr Suresh C Joshi

Effect of an Ayurvedic formulation to increase the life span of Swiss Albino Mice bearing Ehrlich's Ascitic Carcinoma Cells

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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The increase in life span of swiss albino mice in whom EAC (Ehrlich's Ascitic carcinoma) cells was transplanted in abdominal cavity is evaluated in this study. Inoculation of EAC in the abdominal cavity results into development of malignant ascitis. After development of ascitis mice generally die within 15- 20 days. One group of mice were given Ayurvedic medicine before induction of tumor and continued till their death. Results suggested that there was increase in life span of mice who received Avurvedic formulation.

Experimental Studies

*Pamnani G, **Rjfgopalan M, ***Ravishankar B

Effect of Shatavaryadi Churna and Nilotpaladi Anjana on Linganasha - Cataract

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - Cataract, Linganasha, Shatavari, Nilotpal, Anjana, Saurashtri
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Cataract occurs as a result of altered physiological process within the substance of Lens. The earliest symptoms are disturbances, diminution and finally loss of vision. This experimental study was carried out to study the effect of Shatavaryadi Churna and Nilotpaladi Anjana on the experimental cataract produced in animals and to evaluate the anti-cataract activity of the control drug Saurashtri netra bindu. The study shows that Saurashtri Netra Bindu administration may produce good effect in the treatment of developing cataract. Combined therapy has moderate effect and administration of Nilotpaladi Netra Bindu has no effect.

Literary Reviews

*Dr. Nageshwar Rao

HISTORICAL ASPECT OF WASENDRAMANGAL:

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - Rusendramangal (RM)
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In Ayurveda, one can find a lot of classical books in the field of Rasa Sastra. Though in the beginning, our Vaidyas use to treat the patients with mainly herbal drugs, later much emphasis was laid on Herbo-mineral preparations. Rasendramangal is one of those books, which has given a lot of information on various formulations to treate the patients. But now-a-days, this book in not easily available and there is a lot of controversy about it's period and author. So here efforts has been made in this article to look into the historical background of Rasendramangal and to make things dear.

Pharmaceutical Study

*Singh Anita, **Reddy K.R.C., ***Dubey S.D.

Muktashukti in Ayurvedic System of medicine w.s.r.to its Pharmaceutical processing

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - Sudha Varga, Muktashukti Shodhana Marana , Muktashukti Bhasma
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In Ayurveda, Sudha Vargiya (Calcium group) Dravyas are very much popular and some of these drugs used by the Ayurvedic physicians for curing many diseases in different forms. Among Sudha Vargiya Dravyas, Muktashukti plays very important role in Ayurvedic System of Medicine. There is no reference regarding Muktashukti mentioned in Ancient Literature. Shukti is known in India from Samhita period. In Caraka Samhita, Caraka has mentioned Sukti as an ingredient of a Lepa (ointment) used to treat `Rakta Pittavisharpa'. Muktashukti bhasma is used mainely in Udarashula, Jvara, Pitta Jvara, Rakta raga. Here in present study, Muktashukti bhasma has been prepared at 7oo°C temperature subjecting to heat in Electronic Muffle Furnace (EMF) after its proper Shodhana processing.

Pharmaceutical Study

*Vaidya Mita Kotecha, **Vaidya K. Shankar Rao

Amalaki

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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Amalaki, commonly called Amla, is one of the medicinally important household plants. Its fruit is used in various edible products, like Chayavanprash, Murabba etc. Present study is collection of studies on "Amalaki" about its medicinal importance, thus bringing them on one platform. Of various studies on Amalaki, its immunomodulatory effect, Anti-Gastric ulcer, Anti-Oxidant, Reduced Lipid Profile, Cytotoxic effect on tumor cells, Anti-atherosclerotic, Hepato protective, and Anti-inflammatory effect was found.

Conceptual Studies

Gurucharan Bhuyan*, G. Babu**, G. P. Prasad***, Prof M. S. Baghel****

Interpretation of Hypertension in Ayurvedic parlance

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - arterial hypertension, pathogenesis, Samprapti, Avaranauarana
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ABSTRACT

As Gananath Sen stated in his "Pratakshya Shareeram"; due to the time factors and other reasons many new diseases are appearing nowadays. Systemic arterial hypertension became a serious clinical entity of global population in present era. In Ayurvedic classics there is no description about the disease hypertension (Uchcha Raktachapa) as such as described in modern science. So, an effort has been taken to establish the pathogenesis (Samprapti) of hypertension by using the Samprapti of some Ayurvedic entity. In this article, the "Avaranauarana" principle of Vata has been specially illustrated as the Samprapti modality of hypertension.

Conceptual Studies

*Dr. Rajkumar K.C., **Dr. Khandel S.K.

HYPERTENSION-Hetuvipareet Treatment

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

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The Physiopathology of Hypertension based on Tridosha Sidhanta' throws light on 'the treatment principle of this disease in .Ayurvedic perspective. Just as cells are structural and functional units. Panchmahabhoota and Tridosha constitute the structural and functional units in Ayurveda. All the solid and hard substances in a cell are "Parthiva", liquid substances in a cell like fat, water etc. are made up of "Jala", enzymes, acids, hormones that bring about transformation comprise the "Tejasabhuta", impulses which are responsible for all movements in and of the cell are formed of "Vayu" and the spaces in the cell that facilitate unobstructed movements are the contributions of "Akasha". "Parthiva' and `laid effect anabolism. Tejas effects metabolism and' Vayu' and' Akasha' bring about energy utilisation, thereby catabolism. These three factors scientifically termed as ‘Kapha' , Tina' and Tata' respectively are the physiological components in Ayurveda. Hypertension, which is overactivity of circulatory system enhances catabolic activity and could easily be perceived as an aggravated vata disease. As most of the symptoms like pulsating headache. giddiness (bhrama), palpitation(spandanam), insomnia (nidra nasha). nervousness(anavasthita chittata), fatigue (balabhramsha) etc. identify well with the deranged vata symptoms, hypertension in Ayurveda could be considered as a disease of vitiated vata or a Enanatmaja vata vyadhi

Standardization

*J.K.Pattanshetty, **K. GopaKumar, ***G. Venkateswarlu.

Chemical analysis of Boswellia serrata (Gum-resin)

2007   |   July-September   |   VOLUME - I   |   ISSUE - 3

KEYWORDS - Gum, Oleoresin, Boswellic acids, TLC studies.
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The gum-resin of Boswellia serrata is bitter, anti-pyretic, anti-dysenteric, diuretic and analgesic in nature'. In the present paper analytical specifications like physico-chemical analysis and phytochemical studies are provided. The gum contains different sugars. It also contains volatile oil and uronic acids. A range of triterpene acids have been isolated. Viz. P-Boswellic acids, which is responsible for its medicinal value.

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