ISSN:2582-7693

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Journal of Ayurveda

A Peer Reviewed Research Publication of
National Institute of Ayurveda, Jaipur

TABLE OF CONTENT

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

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Editoral Forum

" Vaidya Pawankumar Godatwar

Evidence Based Medicine in context of Ayurveda

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Evidence-based medicine, Evidence-based Ayurveda
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ABSTRACT

The term "evidence-based medicine" (EBM) has gained substantial currency over the last few years. EBM has been described as a "paradigm shift" that will eventually "change medical practice in future." Testing interventions for efficacy has existed since antiquity and Ayurveda cites hundreds of such efficacious remedies, which could only have been drawn as conclusions of extensive clinical trials. Evidence-based medicine categorizes different types of clinical evidence and ranks them according to the strength of their freedom from the various biases that beset medical research. Critics of EBM say lack of evidence and lack of benefit are not the same. Concepts such as "Purusham purusham veekshya..." (Charaka Soo.1/124) and "Doshyam , Desham, Balam, Kaalam....” (Vagbhatta Soo.) does not allow for generalization therefore patients in general and certain groups in particular have been historically under-researched and therefore unsuitable for EBM.

Conceptual Studies

*Dr. M. Dinakara Sharma

Anatomical Elucidation of SHAT CHAKRAS

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Shat Chakra, Plexus, Shushumna, Spinal cord, Mulaadhaara, Anus, Svadhishthana, Genital, Manipura, Navel, Anahata, Heart, Vishudha, Neck, Ajna, Head.
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ABSTRACT

Abstract: There are six chakras in the body. The chakras are centres of Pranashakti. Shakti is extraterrestrial energy in dormant form. They are situated in the body in an ascending manner beginning with the mulaadhaara chakra near the anus, svadhishthana chakra near the genital organ, manipura chakra in the navel, anahata chakra in the heart, vishudha chakra at the root of the neck and the sixth one the ajna chakra in the head between the two eye brows. The junctions of nadis with sushumna nadi are known as Chakras - subtle centers of vital energy. They are situated in various points of Sushumna 1. e. spinal cord. The five regions of the vertebral column i. e. coccygeal, sacral, and lumbar, thorasic and cervical region correspond with the regions of the five Chakras. In this article an attempt has been made to compare the shat chakras with some autonomic nerve plexuses of the body.

Conceptual Studies

*Dr. Naresh Khemani

TMDOSHA AMSAAMSA KALPANA - A tool for the selection of Ayurveda Drugs

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Tridosha, Amsa, Rasa, Guna, Virya, Vipaka, Prabhava.
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ABSTRACT

Doshic influence of the drugs can be a newer tool to select the drug. Though this is practiced silently by the practitioners of Ayurveda no definite method of drug selection is evolved until today. Ayurveda herbs certainly need a definite method of gradation as several drugs are indicated in one disease and one drug is attributed with several pharmaceutical actions. An effort is made in this study to grade plant drugs numerically on the basis of DOSHA AMSA and apply it to the drugs indicated in JVARA. Drugs act both by the virtue of GUNA (RASA, GUNA, VIPAKA and VIRYA) and also by the virtue of DRAVYA proper. Some times they act by the virtue of both GUNA PRABHAVA and DRVYA PRABHAVA. Therefore, it is needed to understand the influence of GUNA specified. RASA / GUNA as seen directly influence the body through DOSHA it is easy to understand its impact on the body in the terms of DOSHA AMSAeffect. This has been achieved by- a simple formulation named as "DOSHA AMSAAMSA KALPANA provides a simpler way to calculate and analyze the effect of the drug on DOSHAS caused by the virtue of GUNA PRABHAVA.

Clinical Studies

*B. M. Singh, **R.D. Sharma

Laja Manda & Peya: A Study on Rehydration & Nutritional Effect in Infantile Diarrhea

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - MASS Drug (Musta, Anardana, Saunth, Saunf and Dhanyaka), Laja Manda, Laja Peya
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ABSTRACT

Actute diarrhea remains a common and life threatening disease among the infants through out the world. Laja Manda (scum) / Peya (scum having small quantity of rice) are used to treat diarrhea, thirst and vomiting. This study was randomized and comparative evaluation was done to find out the efficacy of Laja and Manda in management of diarrhea associated with dehydration. A total of 100 infants, aged 3 to 7 month having actute diarrhea, with or without vomiting and mild to moderate dehydration; comprised into 5 groups 'A' control, '13 Manda, 'C' medicated Laja Manda, `U-Laja Peya, & `E' medicated Laja Manda with 20 infants in each group, (medicated = MASS Drug,). The test recipe was given as per group regimen in a dose of 20 ml/kg/hr (minimum). The effect of recipe, based on scoring system, suggested good effect in group 'C" (55%), group '13' (45%) and group `E' (40%), while the gain in weight, reduction in stool frequency & amount, urine frequency & amount were found highly significant (p <0.001) in groups, relatively. This study revealed that the recipe (medicated Laja Manda) may be the best option to treat acute diarrhea in infants, especially in rural area.

Clinical Studies

* Dr. Seema Jain Bhadora, **Prof Ajay Kumar Sharma

Clinical Evaluation of Hypolipidaemic Activities of Certain Herbo-Mineral Drugs with special reference to Obesity

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - gthaulya, Obesity, meda, Lipid profile, MIL Basti
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ABSTRACT

Sthaulya Raga contributes too much morbidity in the patients and it has been named the mother of Diabetes, Hypertension, Cerebro-vascular disease, Joint-disorders, Hyperlipidaemias & other problems. Sthaulya Roga strikingly resembles with disease entity termed as obesity in Modern system of medicine. The basic principles of treatment of Sthaulya Roga (Obesity) as described in Ayurvedic classics & modern texts of medicine are Nidana parivarjana & Apatarpana cikitsa in the form of consumption of low caloric diet and increase in exercise. In this context, Sodhana cikitsa in the form of Lekhana Basti & Samaria cikitsa in the form of Medohara Bati have been used in the present trial as the remedies for the management of Sthaulya (Obesity). Diet & modified life styles were also advised to the patients of Sthaulya Roga for correction of their body weight & Lipid Profile. The study was conducted in 45 clinically diagnosed patients of Obesity with an objective of clinical evaluation of Hypolipdaemic effect of Medohara Bati & Lekhana Basti (Both Kalpita yoga) on the basis of various scientific parameters. It was observed that the patients treated with trial drugs separately and together showed statistcally highly significant reduction in their body weight 1k correction in Lipid profile. The percentage of improvement was minimum in MedaharaBati treated group & maximum in mixed group. No side/toxic effects were noted in any of the patients during the trial period.

Clinical Studies

*Dr. Amanpreet Kaur Broca, **Dr. Umesh Chandra Sharma, ***Prof Hemant Kumar Kushwaha, ****Prof S. S. Sharma, *****Dr. D.P. Agarwal, ******Dr. Arun Chauguley

Evaluation of Clinical Response of Carcinolyt (Herbal Nutrients) To Control Adverse Effects of Radiotherapy in Cancer Patients

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Herbal, Radioprotective, Cancer, Radiotherapy, Vrana shodhak, Rakta Shodhak, Agnideepak, Balya, Cytotoxic.
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ABSTRACT

The Best in the cancer treatment will come through a combination of conventional and alternative medicine. Ayurveda can play a vital role in palliative, promotive and preventive strategy against cancer. The importance and utility of Ayurveda in cancer management is because there are limitations to the present treatment modalities of this fatal disease, which are well known for their toxic effects and complications. In the present study, an indigenous formulation— Carsinolyt (awaleha & Ghan Satva) was evaluated to prevent side effects of Radiotherapy Trial was done on forty patients, Group A Patients were given carsinolyt and radiotherapy simultaneously whereas Group B patients were given radiotherapy only. The results achieved were encouraging with improvement of 56.62% in mucosal reactions, 37.5% in Haematological status, 18.18% in Pain, 8.33% in Salivary reactions, and 21.42% in Skin reactions. Carsinolyt incorporates Agnidcepak, Amadoshahar, Vrana shodhak, Vrana ropak, Vedna sthapak, Vishaghan, Gandmala Nashak, Mukh shodhak, Raktashodhak & Balya drugs and the reduction of cytotoxic effects of radiotherapy also owe to the same actions. Carsinolyt proved to be non-toxic, immunomodulator, adaptogenic and radioprotective preparation.

Clinical Studies

*Prof M. S. Meena, **Dr. Nand Kishor Dadich

A Clinical study of Shwitra (Vitiligo)

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Shwitra, Ayurvedic drug, Pigmentation, Shwitrakusthari Rasa, Aargvadhadhya Taila.
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ABSTRACT

Shwitra (Vitiligo) is one of the most common skin disorder prevalent now a days. Skin is one of most sensitive organ which plays an important role in health, disease as well as beauty. Even a small lesion on superficial skin can cause a lot of anxiety and depression in several peoples.. Shwitra (Vitiligo) means loss of pigment with white patches of varied sizes often symmetrically distributed. The skin bordering the affected sites is usually hyperpigmented and hair in affected area is usually but not always white. A lot of references are available in different ayurvedic classic which shows that the disease was prevalent in ancient times also. In modern medicine, its exact cause is still unknown and the treatment is not appropriate. But ayurvedic science has answer for this. A lot of research work has also been carried out in context of Shwitra at N.I.A., Jaipur. Slmitrakusthari Rasa and Aargvadhadhya taila were found to be effective in the treatment of Shwitra.

Clinical Studies

*Dr. Nisha K. Ojha, **Dr. Abhimanyu Kumar, ***Dr. Moti Rai

Clincal study of the role of an Ayurvedic compound (Manas Niyamak Yoga) and Shirodhara in the management of ADHD in Children

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Attention Deficit Hyperactivity Disorder (ADHD), Impulsivity, Reaction time, Shirodhara
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ABSTRACT

Attention Deficit Hyperactive disorder is a neurobehavioral disorder of childhood period and characterized by inattention, impulsiveness and hyperactivity. In a randomized double blind placebo controlled study a formulated Ayurvedic compound iManas Niyamak Yoga' has shown statistically significant improvement in the symptoms-inattention, impulsiveness and hyperactivity. However, the response was more marked in the children who received drug along with Shirodhara.

Experimental Studies

*Dr. Anil Mangal, **Prof. Mahesh Chandra Sharma, ***Prof Maheep Bhatnagar

Experimental Evaluation of Antifertility Activity of An Indegenous Drug Vankadali [Ensete Superbum (Roxb.) Cheesman]

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Ensete superburni Antifertility, Testis, Vankadali, Family planning
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ABSTRACT

Present study examines antifertility effect of pseudostem extract of Ensete superbum in male albino rats. Administration of the plant juice extract for 30 days at the dose of 1,2 and 5 ml per day per rat exhibited significant weight loss of genital organs and induced infertility in male rats, without loss of libido as evaluated by sterile matting with normal proestrous females. Decrease in number of spermatozoa in cauda epididymis and morphological changes both in sperm and testis is considered contributory to the Antifertility.

Experimental Studies

*Ravishankar B., *Shukla V. J., ***Subrata De

Ethnopharmacological studies on four medicinal plants

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Jyotismati, Celastrus Paniculatus, Parna Beej, Bryophyllum calycinum, Neelkanthi, Ajuga bracteosa. Lochnera.
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ABSTRACT

Ethnopharmacology can be considered as the study of drugs used for diagnosis, prevention and treatment of disease by different ethnic groups and often outside the framework of mainstream medicine Ethnopharmacology has made significant contribution to the modem medicine. In broader sense even the drugs used in Indian Systems of Medicine (ISM) are grouped under ethnomedicines. Our country is very rich in bio-diversity resources. This has lead to utilization of large number of plants through out the country covering different eco-systems. According to one estimation over 7500 species of plants are estimated to be used by 4635 ethnic communities across the country. This includes around 1700 species used in the preparation of drugs used in ISM. The material is so vast it will be difficult to enumerate and summarize the data available in the published literature in an article of this kind. Hence it was thought useful to present the summarized results and the context in which they were undertaken regarding some of the recent studies undertaken on folklore claim in Gujarat Ayurved University, Jamnagar.

Experimental Studies

*K. Mulye, **S.Tawde, ***P. Shringare, ****R. Deshmukh

Medicinal herbs: Potential Anti-HIV agents?

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Herbal, Phyllanthus amarus, Curcuma longa, Azadirachta indica, HIV, AIDS, Extracts.
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ABSTRACT

The advances and implementation of HAART in the management of HIV/AIDS, has revealed its limitations such as resistant strain development, adverse side effects, lack of definite curative effect, high cost. Hence, the development of novel, safe, effective, low cost medicines is one of the top global priorities. Ayurveda describes traditional herbal remedies for various infectious diseases. Objectives: To study medicinal plants for their inhibitory effects on HIV Reverse Transcriptase Enzyme and envelope antigen gp 120 Methods: Crude, Aqueous, Ethanol extracts were prepared from leaves of Azadirachta indica, Phyllanthus amarus, Rosemary officinalis, rhizome of Curcuma longa, roots and stalon of Glycyrrhiza glabra. In-vitro selective inhibition of viral growth and cytotoxicity associated with the medicinal plants was simultaneously assessed by XTT-Formazan method using H9 cells. The sub-toxic concentration of the prepared extracts were analysed for HIV —RT inhibition using scintillation counting. gpi2o capture ELISA was used for assessing the ability of the plant extract to inhibit interaction of CD4 — gpi2o interaction. Results and Conclusion: Crude extract of Phyllanthus amarus showed the Maximum inhibition (70.31%) of viral RT followed by that of Curcuma longa (67.72 %) and Aqueous extract of Azadirachta indica ( 64.82%). Maximum gpi2o binding inhibition was shown by ethanol extract of Phyllanthus arnarus (94.97%) followed by Aqueous extract of Azadirachta indica (93.09 %). Thus, among the fifteen medicinal plant extracts analysed aqueous extract of Azadirachta indica was found to be superior source of anti-HIV moieties and support further study of the extract for their potential as a new antiretroviral or immunomodulatoty compound.

Literary Reviews

*Girisk K .J, **A B Thakar, ***M S Baghel

Revival of Vajikarana tantra A ready recokner on theses titles of Ayurveda to Vajikarana Tantra over past 45 years

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Vajikarana Tantra, Post Graduate Research theses, Database.
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ABSTRACT

Vajikarana Tantra is one of the specialties among Ashtanga Ayurveda, Post Graduate Research Institutes started research in Vajikarana Tantra since mid of loth century. Such research works are part of measures to revive and to give scientifically convincing outlook to Vajikarana Tantra. In this paper an endeavor has been made to collect and summarize the research work titles on Vajikarana Tantra carried out at various P.G. Institutes of Ayurveda in India over past so years. Search of database identified 120 theses works. Majority of (63%) the theses were written in English language and 38%(45) were contributed in I.P.G.T.& R.A, Gujarat Ayurveda University, Jamnagar, and 12.7% (15) and 11% (14) are submitted at I.M.S., B.1-1.U., Varanasi and N.I.A., Jaipur respectively. Out of these 8 works have been done at Ph.D. level.

Literary Reviews

*Dr. Ramin Mobasseri

Sahaja Yoga — an universal method of stress coping, prevention and treatment of diseases ?

2007   |   January-March   |   VOLUME - I   |   ISSUE - 1

KEYWORDS - Sahaja Yoga, Kundalini, Stress, Chakra.
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ABSTRACT

Sahaja Yoga is a simple and accessible meditation technique which has been found to have long lasting, positive, physiological and psychological effects upon people of all age groups. The technique addresses the physiological being in terms of being dependant upon the subtle balance of the autonomous nervous system. Through the practice of Sahaja Yoga an inner energy called the, `Kundalini" (which is described in ancient Indian texts like the Gyaneshwari) spontaneously becomes awakened and commences a physiological process of re-balancing the complex interrelationships between the; autonomous, sympathetic and parasympathetic nervous systems and the plexuses of the body. The present paper analyses the results of some of the scientific work done on the subject.

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